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|
Factor
| |
Frequency (%)
|
|---|
| | |
MMR deficient
|
MMR proficient
|
|---|
|
Patients (n = 462)
|
Total number
|
103
|
(22.3)
|
359
|
(77.7)
|
|
Sex (n = 462)
|
Male
|
26
|
(25.2)
|
184
|
(51.3)
|
|
Female
|
77
|
(74.8)
|
175
|
(48.7)
|
|
Age (n = 462)
|
Mean
|
76
| |
74
| |
|
Age ≥60
|
102
|
(99.0)
|
328
|
(91.4)
|
|
Tumors (n = 474)
|
Total number
|
108
|
(22.8)
|
366
|
(77.2)
|
|
pT stage (n = 450)
|
pT1
|
2
|
(1.9)
|
6
|
(1.7)
|
| |
pT2
|
10
|
(9.6)
|
37
|
(10.7)
|
| |
pT3
|
87
|
(83.7)
|
224
|
(64.8)
|
| |
pT4
|
5
|
(4.8)
|
79
|
(22.8)
|
|
pN stage (n = 461)
|
pN0
|
76
|
(73.1)
|
183
|
(51.2)
|
| |
pN1
|
23
|
(22.1)
|
107
|
(30.0)
|
| |
pN2
|
5
|
(4.8)
|
67
|
(18.8)
|
|
pM stage (n = 474)
|
pM1
|
1
|
(0.9)
|
10
|
(2.7)
|
|
Differentiation (n = 474)
|
Good/moderate
|
42
|
(38.9)
|
334
|
(91.3)
|
|
Poor/no
|
66
|
(61.1)
|
32
|
(8.7)
|
|
Location (n = 473)
|
Proximal
|
99
|
(91.7)
|
173
|
(47.4)
|
|
Distal
|
9
|
(8.3)
|
192
|
(52.6)
|
|
Growth pattern (n = 459)
|
Expanding
|
76
|
(73.8)
|
27
|
(7.6)
|
|
Infiltrating
|
27
|
(26.2)
|
329
|
(92.4)
|
|
Dirty necrosis (n = 467)
|
Present
|
20
|
(19.4)
|
269
|
(73.9)
|
|
Absent
|
83
|
(80.6)
|
95
|
(26.1)
|
|
Mucin/signet-ring differentiation (n = 473)
|
Present (>50%)
|
23
|
(21.3)
|
15
|
(4.1)
|
|
Present (10-50%)
|
50
|
(46.3)
|
81
|
(22.2)
|
|
Absent
|
35
|
(32.4)
|
269
|
(73.7)
|
|
TIL (n = 470)
|
Present
|
72
|
(66.7)
|
61
|
(16.9)
|
|
Absent
|
36
|
(33.3)
|
301
|
(83.1)
|
-
Abbreviations: MMR mismatch repair, TIL tumor-infiltrating lymphocytes.
