You are viewing the site in preview mode

Skip to main content

Table 3 Univariate analyses of disease progresssion (n =158)

From: Expression of histone deacetylases 1, 2 and 3 in urothelial bladder cancer

Variable Categorization Tumor progression
na events pb
Pathologic data:    
Tumor stage (WHO 1973c)    
  pTa 85 10 0.412
  pT1 68 12  
Histologic grade (WHO 1973c)    
  G1 43 3 0.093
  G2 82 12  
  G3 28 7  
Histologic grade (WHO 2004d)    
  Low grade 95 10 0.092
  High grade 58 12  
Adjacent carcinoma in situ    
  No 141 20 0.570
  Yes 12 2  
Multifocality    
  Unifocal tumor 111 15 0.486
  Multifocal tumor 42 7  
Growth pattern    
  Papillary 146 17 <0.0001
  Solid 7 5  
Immunohistochemistry:    
HDAC-1     
  Low expression 92 9 0.085
  High expression 61 13  
HDAC-2     
  Low expression 88 12 0.628
  High expression 65 10  
HDAC-3     
  Low expression 65 8 0.754
  High expression 88 14  
Ki-67 IHC     
  Low expression 101 9 0.004
  High expression 52 13  
  1. aOnly primary pTa and pT1 tumours are included.
  2. bLog Rank test (2-sided); bold face representing p-values <0.05.
  3. cStaging and grading according to the 1973 WHO classification system.
  4. dStaging and grading according to the 2004 WHO classification system.
Back to article page

BMC Clinical Pathology

ISSN: 1472-6890

Contact us